Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs

Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs

The RNA-binding protein AUF1 binds AU-rich elements in 3′-untranslated regions to regulate mRNA degradation and/or translation. Many of these mRNAs are predicted microRNA targets as well. An emerging theme in post-transcriptional control of gene expression is that RNA-binding proteins and microRNAs...

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Bibliographic Details
Main Authors: Wu, Xiangyue, Chesoni, Sandra, Rondeau, Gaelle, Tempesta, Christi, Patel, Reshma, Charles, Sandy, Daginawala, Naznin, Zucconi, Beth E., Kishor, Aparna, Xu, Guangwu, Shi, Yufang, Li, Mei-Ling, Irizarry-Barreto, Patricia, Welsh, John, Wilson, Gerald M., Brewer, Gary
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575833/

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