Reduced Syncytin-1 Expression Levels in Placental Syndromes Correlates with Epigenetic Hypermethylation of the ERVW-1 Promoter Region

Terminal differentiation of villous cytotrophoblasts (CT) ends in formation of the multinucleated syncytiotrophoblast representing the fetal-maternal interface. Aberrations during this cell-fusion process are associated with Intrauterine Growth Restriction (IUGR), Preeclampsia (PE) and High Elevated...

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Bibliographic Details
Main Authors: Ruebner, Matthias, Strissel, Pamela L., Ekici, Arif B., Stiegler, Elisabeth, Dammer, Ulf, Goecke, Tamme W., Faschingbauer, Florian, Fahlbusch, Fabian B., Beckmann, Matthias W., Strick, Reiner
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573012/