Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene

Integration of Mouse and Human Genome-Wide Association Data Identifies KCNIP4 as an Asthma Gene

Asthma is a common chronic respiratory disease characterized by airway hyperresponsiveness (AHR). The genetics of asthma have been widely studied in mouse and human, and homologous genomic regions have been associated with mouse AHR and human asthma-related phenotypes. Our goal was to identify asthm...

Full description

Bibliographic Details
Main Authors: Himes, Blanca E., Sheppard, Keith, Berndt, Annerose, Leme, Adriana S., Myers, Rachel A., Gignoux, Christopher R., Levin, Albert M., Gauderman, W. James, Yang, James J., Mathias, Rasika A., Romieu, Isabelle, Torgerson, Dara G., Roth, Lindsey A., Huntsman, Scott, Eng, Celeste, Klanderman, Barbara, Ziniti, John, Senter-Sylvia, Jody, Szefler, Stanley J., Lemanske, Robert F., Zeiger, Robert S., Strunk, Robert C., Martinez, Fernando D., Boushey, Homer, Chinchilli, Vernon M., Israel, Elliot, Mauger, David, Koppelman, Gerard H., Postma, Dirkje S., Nieuwenhuis, Maartje A. E., Vonk, Judith M., Lima, John J., Irvin, Charles G., Peters, Stephen P., Kubo, Michiaki, Tamari, Mayumi, Nakamura, Yusuke, Litonjua, Augusto A., Tantisira, Kelan G., Raby, Benjamin A., Bleecker, Eugene R., Meyers, Deborah A., London, Stephanie J., Barnes, Kathleen C., Gilliland, Frank D., Williams, L. Keoki, Burchard, Esteban G., Nicolae, Dan L., Ober, Carole, DeMeo, Dawn L., Silverman, Edwin K., Paigen, Beverly, Churchill, Gary, Shapiro, Steve D., Weiss, Scott T.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572953/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572953/

Similar Items