Current Status of Photodynamic Therapy for Bile Duct Cancer
The most common form in bile duct cancers is a highly desmoplastic cancer with a growth pattern characterized by periductal extension and infiltration. The prognosis of bile duct cancers, especially hilar cholangiocarcinoma, is limited by tumor spread along the biliary tree leading to refractory obs...
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The Korean Society of Gastrointestinal Endoscopy
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572349/ |
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pubmed-35723492013-02-19 Current Status of Photodynamic Therapy for Bile Duct Cancer Lee, Tae Yoon Cheon, Young Koog Shim, Chan Sup Focused Review Series: Photodynamic Therapy The most common form in bile duct cancers is a highly desmoplastic cancer with a growth pattern characterized by periductal extension and infiltration. The prognosis of bile duct cancers, especially hilar cholangiocarcinoma, is limited by tumor spread along the biliary tree leading to refractory obstructive cholestasis, cholangitis, and liver failure. Although biliary endoprosthesis improves occlusion rates and reduces the number of therapeutic interventions, median survival time is not ameliorated. Photodynamic therapy (PDT) is a local photochemical tumor treatment that consists of a photosensitizing agent in combination with laser irradiation of a distinct wavelength. Tumor ablation with PDT combined with biliary stenting reduces cholestasis and significantly improves median survival time in selected patients with bile duct cancers. The Korean Society of Gastrointestinal Endoscopy 2013-01 2013-01-31 /pmc/articles/PMC3572349/ /pubmed/23423177 http://dx.doi.org/10.5946/ce.2013.46.1.38 Text en Copyright © 2013 Korean Society of Gastrointestinal Endoscopy http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Lee, Tae Yoon Cheon, Young Koog Shim, Chan Sup |
| spellingShingle |
Lee, Tae Yoon Cheon, Young Koog Shim, Chan Sup Current Status of Photodynamic Therapy for Bile Duct Cancer |
| author_facet |
Lee, Tae Yoon Cheon, Young Koog Shim, Chan Sup |
| author_sort |
Lee, Tae Yoon |
| title |
Current Status of Photodynamic Therapy for Bile Duct Cancer |
| title_short |
Current Status of Photodynamic Therapy for Bile Duct Cancer |
| title_full |
Current Status of Photodynamic Therapy for Bile Duct Cancer |
| title_fullStr |
Current Status of Photodynamic Therapy for Bile Duct Cancer |
| title_full_unstemmed |
Current Status of Photodynamic Therapy for Bile Duct Cancer |
| title_sort |
current status of photodynamic therapy for bile duct cancer |
| description |
The most common form in bile duct cancers is a highly desmoplastic cancer with a growth pattern characterized by periductal extension and infiltration. The prognosis of bile duct cancers, especially hilar cholangiocarcinoma, is limited by tumor spread along the biliary tree leading to refractory obstructive cholestasis, cholangitis, and liver failure. Although biliary endoprosthesis improves occlusion rates and reduces the number of therapeutic interventions, median survival time is not ameliorated. Photodynamic therapy (PDT) is a local photochemical tumor treatment that consists of a photosensitizing agent in combination with laser irradiation of a distinct wavelength. Tumor ablation with PDT combined with biliary stenting reduces cholestasis and significantly improves median survival time in selected patients with bile duct cancers. |
| publisher |
The Korean Society of Gastrointestinal Endoscopy |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572349/ |
| _version_ |
1611954866709594112 |