Proprotein Convertase Furin Regulates Apoptosis and Proliferation of Granulosa Cells in the Rat Ovary

Folliculogenesis is tightly controlled by a series of hormones, growth factors and cytokines, many of which are secreted as proproteins and require processing by proteases before becoming functional. Furin is a member of the subtilisin-like proteases that activate large numbers of proprotein substra...

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Bibliographic Details
Main Authors: Yang, Xiaokui, Wang, Qingxin, Gao, Zhiying, Zhou, Zhi, Peng, Sha, Chang, Wen-Lin, Lin, Hai-Yan, Zhang, Weiyuan, Wang, Hongmei
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572104/