Krüppel-Like Factor 4 Acts as an Oncogene in Colon Cancer Stem Cell-Enriched Spheroid Cells

Cancer stem cells (CSCs), a rare population in any type of cancers, including colon cancer, are tumorigenic. It has been thought that CSCs are responsible for cancer recurrence, metastasis, and drug resistance. Isolating CSCs in colon cancers is challenging, and thus the molecular mechanism regulati...

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Bibliographic Details
Main Authors: Leng, Zhengwei, Tao, Kaixiong, Xia, Qinghua, Tan, Jun, Yue, Zhongyi, Chen, Jinhuang, Xi, Hailin, Li, Jie, Zheng, Hai
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572033/