Exploring the effects of polymorphisms on cis-regulatory signal transduction response

cis-Regulatory sequences (CRSs) direct cell-specific and inducible gene expression in response to signal transduction networks, and it is becoming apparent that many cases of disease susceptibility and drug response stratification are due to polymorphisms that alter CRS responses in a context-depend...

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Bibliographic Details
Main Authors: MacKenzie, Alasdair, Hing, Benjamin, Davidson, Scott
Format: Online
Language:English
Published: Elsevier Science Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569712/