Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3-only proteins Bim and Bmf

Anti-apoptotic Bcl-2 family members are critical for the regulation of haematopoietic stem and progenitor cell (HSPC) survival. Little is known about the role of their pro-apoptotic antagonists, i.e. ‘BH3-only’ proteins, in this cell compartment. Based on the analysis of cytokine deprivation-induced...

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Bibliographic Details
Main Authors: Labi, Verena, Bertele, Daniela, Woess, Claudia, Tischner, Denise, Bock, Florian J, Schwemmers, Sven, Pahl, Heike L, Geley, Stephan, Kunze, Mirjam, Niemeyer, Charlotte M, Villunger, Andreas, Erlacher, Miriam
Format: Online
Language:English
Published: WILEY-VCH Verlag 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569658/