The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes
Mitochondrial-dependent (intrinsic) programmed cell death (PCD) is an essential homoeostatic mechanism that selects bioenergetically proficient cells suitable for tissue/organ development. However, the link between mitochondrial dysfunction, intrinsic apoptosis and developmental anomalies has not be...
Main Authors: | , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
WILEY-VCH Verlag
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569643/ |