Modulators of HIF1α and NFkB in Cancer Treatment: Is it a Rational Approach for Controlling Malignant Progression?

Modulators of HIF1α and NFkB in Cancer Treatment: Is it a Rational Approach for Controlling Malignant Progression?

HIF1α and NFkB are two transcription factors very frequently activated in tumors and involved in tumor growth, progression, and resistance to chemotherapy. In fact, HIF1α and NFkB together regulate transcription of over a thousand genes that, in turn, control vital cellular processes such as adaptat...

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Bibliographic Details
Main Authors: Tafani, Marco, Pucci, Bruna, Russo, Andrea, Schito, Luana, Pellegrini, Laura, Perrone, Giulietta A., Villanova, Lidia, Salvatori, Luisa, Ravenna, Linda, Petrangeli, Elisa, Russo, Matteo A.
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569619/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569619/

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