Carbon Ion Radiotherapy for Oligo-Recurrence in the Lung
The clinical results after carbon ion radiotherapy for the metastatic lung tumors believed to be in the state of oligo-recurrence were evaluated. One hundred and sixteen lesions in 91 patients with lung cancer metastasis were treated with carbon ion radiotherapy at our institute from April 1997 to F...
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| Format: | Online |
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Hindawi Publishing Corporation
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568897/ |
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pubmed-35688972013-02-21 Carbon Ion Radiotherapy for Oligo-Recurrence in the Lung Yamamoto, Naoyoshi Nakajima, Mio Tsujii, Hirohiko Kamada, Tadashi Clinical Study The clinical results after carbon ion radiotherapy for the metastatic lung tumors believed to be in the state of oligo-recurrence were evaluated. One hundred and sixteen lesions in 91 patients with lung cancer metastasis were treated with carbon ion radiotherapy at our institute from April 1997 to February 2011. Regarding the prescribed dose, total dose ranged between 40 gray equivalents (GyE) and 80 GyE, and fraction size ranged from 1 to 16 fractions. After a median followup period of 2.3 years (range, 0.3–13.1 years), the statistical overall survival rate and local control rate were 71.2% and 91.9% at 2 years after treatment, respectively. Treatment-related side effects were not a clinical problem. When classified by the primary organ, there were 49 cases of lung cancer, 20 cases of colorectal cancer, and 22 cases of others. The overall survival rate and local control rate for lung metastasis cases from lung cancer at 2 years after treatment were 81.5% and 92.4%, respectively, and 65.0% and 92.0% regarding lung metastasis from colorectal cancer. Carbon ion beam therapy for the metastatic lung tumors is a safe therapy, and the therapeutic effect is comparable to the outcome obtained from reported surgical resections. Hindawi Publishing Corporation 2013 2013-01-27 /pmc/articles/PMC3568897/ /pubmed/23431437 http://dx.doi.org/10.1155/2013/219746 Text en Copyright © 2013 Naoyoshi Yamamoto et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Yamamoto, Naoyoshi Nakajima, Mio Tsujii, Hirohiko Kamada, Tadashi |
| spellingShingle |
Yamamoto, Naoyoshi Nakajima, Mio Tsujii, Hirohiko Kamada, Tadashi Carbon Ion Radiotherapy for Oligo-Recurrence in the Lung |
| author_facet |
Yamamoto, Naoyoshi Nakajima, Mio Tsujii, Hirohiko Kamada, Tadashi |
| author_sort |
Yamamoto, Naoyoshi |
| title |
Carbon Ion Radiotherapy for Oligo-Recurrence in the Lung |
| title_short |
Carbon Ion Radiotherapy for Oligo-Recurrence in the Lung |
| title_full |
Carbon Ion Radiotherapy for Oligo-Recurrence in the Lung |
| title_fullStr |
Carbon Ion Radiotherapy for Oligo-Recurrence in the Lung |
| title_full_unstemmed |
Carbon Ion Radiotherapy for Oligo-Recurrence in the Lung |
| title_sort |
carbon ion radiotherapy for oligo-recurrence in the lung |
| description |
The clinical results after carbon ion radiotherapy for the metastatic lung tumors believed to be in the state of oligo-recurrence were evaluated. One hundred and sixteen lesions in 91 patients with lung cancer metastasis were treated with carbon ion radiotherapy at our institute from April 1997 to February 2011. Regarding the prescribed dose, total dose ranged between 40 gray equivalents (GyE) and 80 GyE, and fraction size ranged from 1 to 16 fractions. After a median followup period of 2.3 years (range, 0.3–13.1 years), the statistical overall survival rate and local control rate were 71.2% and 91.9% at 2 years after treatment, respectively. Treatment-related side effects were not a clinical problem. When classified by the primary organ, there were 49 cases of lung cancer, 20 cases of colorectal cancer, and 22 cases of others. The overall survival rate and local control rate for lung metastasis cases from lung cancer at 2 years after treatment were 81.5% and 92.4%, respectively, and 65.0% and 92.0% regarding lung metastasis from colorectal cancer. Carbon ion beam therapy for the metastatic lung tumors is a safe therapy, and the therapeutic effect is comparable to the outcome obtained from reported surgical resections. |
| publisher |
Hindawi Publishing Corporation |
| publishDate |
2013 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3568897/ |
| _version_ |
1611953754067697664 |