Multiple Genetic Alterations within the PI3K Pathway Are Responsible for AKT Activation in Patients with Ovarian Carcinoma

Multiple Genetic Alterations within the PI3K Pathway Are Responsible for AKT Activation in Patients with Ovarian Carcinoma

The phosphatidylinositol 3-kinase (PI3K)/AKT pathway is activated in multiple cancers including ovarian carcinoma (OC). However, the relative contribution of the single components within the PI3K pathway to AKT activation in OC is still unclear. We examined 98 tumor samples from Italian OC patients...

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Bibliographic Details
Main Authors: De Marco, Carmela, Rinaldo, Nicola, Bruni, Paola, Malzoni, Carmine, Zullo, Fulvio, Fabiani, Fernanda, Losito, Simona, Scrima, Marianna, Marino, Federica Zito, Franco, Renato, Quintiero, Alfina, Agosti, Valter, Viglietto, Giuseppe
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567053/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567053/

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