Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts
NCLs (neuronal ceroid lipofuscinoses) form a group of eight inherited autosomal recessive diseases characterized by the intralysosomal accumulation of autofluorescent pigments, called ceroids. Recent data suggest that the pathogenesis of NCL is associated with the appearance of fragmented mitochondr...
| Main Authors: | , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566540/ |