Nonstructural Protein 1 of Influenza A Virus Interacts with Human Guanylate-Binding Protein 1 to Antagonize Antiviral Activity

Nonstructural Protein 1 of Influenza A Virus Interacts with Human Guanylate-Binding Protein 1 to Antagonize Antiviral Activity

Human guanylate-binding protein 1 (hGBP1) is an interferon-inducible protein involved in the host immune response against viral infection. In response to infection by influenza A virus (IAV), hGBP1 transcript and protein were significantly upregulated. Overexpression of hGBP1 inhibited IAV replicati...

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Bibliographic Details
Main Authors: Zhu, Zixiang, Shi, Zixue, Yan, Wenjun, Wei, Jianchao, Shao, Donghua, Deng, Xufang, Wang, Shaohui, Li, Beibei, Tong, Guangzhi, Ma, Zhiyong
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566120/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566120/

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