Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations

A population of mouse embryonic stem (ES) cells is characterized by a distribution of Nanog, a gene whose expression is associated with the degree of pluripotency. Cells exhibiting high levels of Nanog maintain a state of pluripotency, while those with low levels are more likely to undergo different...

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Bibliographic Details
Main Authors: Luo, Yang, Lim, Chea Lu, Nichols, Jennifer, Martinez-Arias, Alfonso, Wernisch, Lorenz
Format: Online
Language:English
Published: The Royal Society 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565777/