Nitric Oxide Synthesis Is Increased in Cybrid Cells with m.3243A>G Mutation

Nitric oxide (NO) is a free radical and a signaling molecule in several pathways, produced by nitric oxide synthase (NOS) from the conversion of l-arginine to citrulline. Supplementation of l-arginine has been used to treat MELAS (mitochondrial encephalopathy with lactic acidosis and stroke like syn...

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Bibliographic Details
Main Authors: Gamba, Juliana, Gamba, Luana T., Rodrigues, Gabriela S., Kiyomoto, Beatriz H., Moraes, Carlos T., Tengan, Celia H.
Format: Online
Language:English
Published: MDPI 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565270/