The voltage-dependent gate in MthK potassium channels is located at the selectivity filter

Understanding how ion channels open and close their pores is crucial for understanding their physiological roles. We used intracellular quaternary ammonium blockers to locate the voltage-dependent gate in MthK potassium channels from Methanobacterium thermoautotrophicum with electrophysiology and X-...

Full description

Bibliographic Details
Main Authors: Posson, David J., McCoy, Jason G., Nimigean, Crina M.
Format: Online
Language:English
Published: 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565016/