Human MicroRNAs Originated from Two Periods at Accelerated Rates in Mammalian Evolution

MicroRNAs (miRNAs) are short, noncoding RNAs that modulate genes posttranscriptionally. Frequent gains and losses of miRNA genes have been reported to occur during evolution. However, little is known systematically about the periods of evolutionary origin of the present miRNA gene repertoire of an e...

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Bibliographic Details
Main Authors: Iwama, Hisakazu, Kato, Kiyohito, Imachi, Hitomi, Murao, Koji, Masaki, Tsutomu
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563971/