Effect of High-Dose or Split-Dose Artesunate on Parasite Clearance in Artemisinin-Resistant Falciparum Malaria

Effect of High-Dose or Split-Dose Artesunate on Parasite Clearance in Artemisinin-Resistant Falciparum Malaria

New treatment strategies are needed for artemisinin-resistant falciparum malaria. This randomized trial shows that neither increasing nor splitting the standard once-daily artesunate dose reverses the markedly reduced parasite clearance rate in patients with artemisinin-resistant falciparum malaria.

Bibliographic Details
Main Authors: Das, Debashish, Tripura, Rupam, Phyo, Aung Pyae, Lwin, Khin Maung, Tarning, Joel, Lee, Sue J., Hanpithakpong, Warunee, Stepniewska, Kasia, Menard, Didier, Ringwald, Pascal, Silamut, Kamolrat, Imwong, Mallika, Chotivanich, Kesinee, Yi, Poravuth, Day, Nicholas P. J., Lindegardh, Niklas, Socheat, Duong, Nguon, Chea, White, Nicholas J., Nosten, François, Dondorp, Arjen M.
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563392/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563392/

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