The mTOR Pathway and the Role of Energy Balance Throughout Life in Colorectal Cancer Etiology and Prognosis: Unravelling Mechanisms Through a Multidimensional Molecular Epidemiologic Approach

Timing of exposure to lifestyle factors that influence energy balance may differentially affect colorectal cancer (CRC) risk and prognosis. Caloric restriction in youth and short stature, as markers of early-life exposures, have shown to decrease CRC risk, whereas large body size and low physical ac...

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Bibliographic Details
Main Authors: Weijenberg, Matty P., Hughes, Laura A. E., Bours, Martijn J. L., Simons, Colinda C. J. M., van Engeland, Manon, van den Brandt, Piet A.
Format: Online
Language:English
Published: Current Science Inc. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562550/