The association of heavy and light chain variable domains in antibodies: implications for antigen specificity
The antigen-binding site of immunoglobulins is formed by six regions, three from the light and three from the heavy chain variable domains, which, on association of the two chains, form the conventional antigen-binding site of the antibody. The mode of interaction between the heavy and light chain v...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Blackwell Publishing Ltd
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562479/ |