Dectin-1 Is Required for Resistance to Coccidioidomycosis in Mice
We assessed the role of Dectin-1 in the immune response to the pathogenic fungus Coccidioides, both in vitro and in vivo, using mice with a targeted mutation in Clec7a. Elicited peritoneal macrophages responded to formalin-killed spherules (FKS) and alkali-treated FKS by secreting proinflammatory cy...
| Main Authors: | , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
American Society of Microbiology
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562125/ |