Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells

Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells

The discovery of direct cell reprogramming and induced pluripotent stem (iPS) cell technology opened up new avenues for the application of non-viral, transposon-based gene delivery systems. The Sleeping Beauty (SB) transposon is highly advanced for versatile genetic manipulations in mammalian cells....

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Bibliographic Details
Main Authors: Grabundzija, Ivana, Wang, Jichang, Sebe, Attila, Erdei, Zsuzsanna, Kajdi, Robert, Devaraj, Anantharam, Steinemann, Doris, Szuhai, Károly, Stein, Ulrike, Cantz, Tobias, Schambach, Axel, Baum, Christopher, Izsvák, Zsuzsanna, Sarkadi, Balázs, Ivics, Zoltán
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561994/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561994/

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