A novel mechanism of eukaryotic translation initiation that is neither m7G-cap-, nor IRES-dependent

Resistance of translation of some eukaryotic messenger RNAs (mRNAs) to inactivation of the cap-binding factor eIF4E under unfavorable conditions is well documented. To date, it is the mechanism of internal ribosome entry that is predominantly thought to underlay this stress tolerance. However, many...

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Bibliographic Details
Main Authors: Terenin, Ilya M., Andreev, Dmitri E., Dmitriev, Sergey E., Shatsky, Ivan N.
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561988/