Improving detection of copy-number variation by simultaneous bias correction and read-depth segmentation

Improving detection of copy-number variation by simultaneous bias correction and read-depth segmentation

Structural variation is an important class of genetic variation in mammals. High-throughput sequencing (HTS) technologies promise to revolutionize copy-number variation (CNV) detection but present substantial analytic challenges. Converging evidence suggests that multiple types of CNV-informative da...

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Bibliographic Details
Main Authors:	Szatkiewicz, Jin P., Wang, WeiBo, Sullivan, Patrick F., Wang, Wei, Sun, Wei
Format:	Online
Language:	English
Published:	Oxford University Press 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561969/

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