McGenus: a Monte Carlo algorithm to predict RNA secondary structures with pseudoknots

We present McGenus, an algorithm to predict RNA secondary structures with pseudoknots. The method is based on a classification of RNA structures according to their topological genus. McGenus can treat sequences of up to 1000 bases and performs an advanced stochastic search of their minimum free ener...

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Bibliographic Details
Main Authors: Bon, Michaël, Micheletti, Cristian, Orland, Henri
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561945/