Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes

Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes

Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ) in the brain because of an imbalance between Aβ production and clearance. Neprilysin (NEP) is the most important Aβ-degrading enzyme in the brain. Thus, researchers have explored virus-mediated NEP gene deli...

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Bibliographic Details
Main Authors: Katsuda, Takeshi, Tsuchiya, Reiko, Kosaka, Nobuyoshi, Yoshioka, Yusuke, Takagaki, Kentaro, Oki, Katsuyuki, Takeshita, Fumitaka, Sakai, Yasuyuki, Kuroda, Masahiko, Ochiya, Takahiro
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561625/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561625/

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