An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication

Ebolaviruses, highly lethal zoonotic pathogens, possess longer genomes than most other non-segmented negative-strand RNA viruses due in part to long 5′ and 3′ untranslated regions (UTRs) present in the seven viral transcriptional units. To date, specific functions have not been assigned to these UTR...

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Bibliographic Details
Main Authors: Shabman, Reed S., Hoenen, Thomas, Groseth, Allison, Jabado, Omar, Binning, Jennifer M., Amarasinghe, Gaya K., Feldmann, Heinz, Basler, Christopher F.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561295/