Cyclosporine A Impairs Nucleotide Binding Oligomerization Domain (Nod1)-Mediated Innate Antibacterial Renal Defenses in Mice and Human Transplant Recipients

Cyclosporine A Impairs Nucleotide Binding Oligomerization Domain (Nod1)-Mediated Innate Antibacterial Renal Defenses in Mice and Human Transplant Recipients

Acute pyelonephritis (APN), which is mainly caused by uropathogenic Escherichia coli (UPEC), is the most common bacterial complication in renal transplant recipients receiving immunosuppressive treatment. However, it remains unclear how immunosuppressive drugs, such as the calcineurin inhibitor cycl...

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Bibliographic Details
Main Authors: Tourneur, Emilie, Ben Mkaddem, Sanae, Chassin, Cécilia, Bens, Marcelle, Goujon, Jean-Michel, Charles, Nicolas, Pellefigues, Christophe, Aloulou, Meryem, Hertig, Alexandre, Monteiro, Renato C., Girardin, Stephen E., Philpott, Dana J., Rondeau, Eric, Elbim, Carole, Werts, Catherine, Vandewalle, Alain
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561241/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561241/

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