A review of subclavian steal syndrome with clinical correlation

Subclavian ‘steal’ phenomenon is a function of the proximal subclavian artery (SA) steno-occlusive disease, with subsequent retrograde blood flow in the ipsilateral vertebral artery (VA). The symptoms from the compromised vertebrobasilar and brachial blood flows constitute the subclavian steal syndr...

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Main Authors: Osiro, Stephen, Zurada, Anna, Gielecki, Jerzy, Shoja, Mohammadali M., Tubbs, R. Shane, Loukas, Marios
Format: Online
Language:English
Published: International Scientific Literature, Inc. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560638/
id pubmed-3560638
recordtype oai_dc
spelling pubmed-35606382013-04-24 A review of subclavian steal syndrome with clinical correlation Osiro, Stephen Zurada, Anna Gielecki, Jerzy Shoja, Mohammadali M. Tubbs, R. Shane Loukas, Marios Review Article Subclavian ‘steal’ phenomenon is a function of the proximal subclavian artery (SA) steno-occlusive disease, with subsequent retrograde blood flow in the ipsilateral vertebral artery (VA). The symptoms from the compromised vertebrobasilar and brachial blood flows constitute the subclavian steal syndrome (SSS), and include paroxysmal vertigo, drop attacks and/or arm claudication. Once thought to be rare, the emergence of new imaging techniques has drastically improved its diagnosis and prevalence. The syndrome, however, remains characteristically asymptomatic and solely poses no serious danger to the brain. Recent studies have shown a linear correlation between increasing arm blood pressure difference with the occurrence of symptoms. Atherosclerosis of the SA remains the most common cause. Doppler ultrasound is a useful screening tool, but the diagnosis must be confirmed by CT or MR angiography. Conservative treatment is the initial best therapy for this syndrome, with surgery reserved for refractory symptomatic cases. Percutaneous angioplasty and stenting, rather than bypass grafts of the subclavian artery, is the widely favored surgical approach. Nevertheless, large, prospective, randomized, controlled trials are needed to compare the long-term patency rates between the endovascular and open surgical techniques. International Scientific Literature, Inc. 2012-05-01 /pmc/articles/PMC3560638/ /pubmed/22534720 http://dx.doi.org/10.12659/MSM.882721 Text en © Med Sci Monit, 2012 This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Osiro, Stephen
Zurada, Anna
Gielecki, Jerzy
Shoja, Mohammadali M.
Tubbs, R. Shane
Loukas, Marios
spellingShingle Osiro, Stephen
Zurada, Anna
Gielecki, Jerzy
Shoja, Mohammadali M.
Tubbs, R. Shane
Loukas, Marios
A review of subclavian steal syndrome with clinical correlation
author_facet Osiro, Stephen
Zurada, Anna
Gielecki, Jerzy
Shoja, Mohammadali M.
Tubbs, R. Shane
Loukas, Marios
author_sort Osiro, Stephen
title A review of subclavian steal syndrome with clinical correlation
title_short A review of subclavian steal syndrome with clinical correlation
title_full A review of subclavian steal syndrome with clinical correlation
title_fullStr A review of subclavian steal syndrome with clinical correlation
title_full_unstemmed A review of subclavian steal syndrome with clinical correlation
title_sort review of subclavian steal syndrome with clinical correlation
description Subclavian ‘steal’ phenomenon is a function of the proximal subclavian artery (SA) steno-occlusive disease, with subsequent retrograde blood flow in the ipsilateral vertebral artery (VA). The symptoms from the compromised vertebrobasilar and brachial blood flows constitute the subclavian steal syndrome (SSS), and include paroxysmal vertigo, drop attacks and/or arm claudication. Once thought to be rare, the emergence of new imaging techniques has drastically improved its diagnosis and prevalence. The syndrome, however, remains characteristically asymptomatic and solely poses no serious danger to the brain. Recent studies have shown a linear correlation between increasing arm blood pressure difference with the occurrence of symptoms. Atherosclerosis of the SA remains the most common cause. Doppler ultrasound is a useful screening tool, but the diagnosis must be confirmed by CT or MR angiography. Conservative treatment is the initial best therapy for this syndrome, with surgery reserved for refractory symptomatic cases. Percutaneous angioplasty and stenting, rather than bypass grafts of the subclavian artery, is the widely favored surgical approach. Nevertheless, large, prospective, randomized, controlled trials are needed to compare the long-term patency rates between the endovascular and open surgical techniques.
publisher International Scientific Literature, Inc.
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560638/
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