Detection of Histone Modifications at Specific Gene Loci in Single Cells in Histological Sections

Chromatin immunoprecipitation (ChIP) assays have contributed greatly to our understanding of the role of histone modifications in gene regulation. However, a major limitation is that they do not permit analysis with single cell resolution thus confounding analyses of heterogeneous cell populations....

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Bibliographic Details
Main Authors: Gomez, Delphine, Shankman, Laura L, Nguyen, Anh T, Owens, Gary K
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560316/