Expression of AFP and STAT3 Is Involved in Arsenic Trioxide-Induced Apoptosis and Inhibition of Proliferation in AFP-Producing Gastric Cancer Cells

Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC), represented by the production of AFP, has a more aggressive behavior than common gastric cancer. The underlying mechanisms are not well understood. Arsenic trioxide (As2O3) is used clinically to treat acute promyelocytic leukemia(APL) and has...

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Bibliographic Details
Main Authors: Jia, Yanfei, Liu, Dezhi, Xiao, Dongjie, Ma, Xiaoli, Han, Shuyi, Zheng, Yan, Sun, Shanhui, Zhang, Maoxiu, Gao, Hongmei, Cui, Xia, Wang, Yunshan
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559880/