Measuring Airway Surface Liquid Depth in Ex Vivo Mouse Airways by X-Ray Imaging for the Assessment of Cystic Fibrosis Airway Therapies

Measuring Airway Surface Liquid Depth in Ex Vivo Mouse Airways by X-Ray Imaging for the Assessment of Cystic Fibrosis Airway Therapies

In the airways of those with cystic fibrosis (CF), the leading pathophysiological hypothesis is that an ion channel defect results in a relative decrease in airway surface liquid (ASL) volume, producing thick and sticky mucus that facilitates the establishment and progression of early fatal lung dis...

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Bibliographic Details
Main Authors: Morgan, Kaye S., Donnelley, Martin, Paganin, David M., Fouras, Andreas, Yagi, Naoto, Suzuki, Yoshio, Takeuchi, Akihisa, Uesugi, Kentaro, Boucher, Richard C., Parsons, David W., Siu, Karen K. W.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559635/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559635/

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