cAMP Elevation Down-Regulates β3 Integrin and Focal Adhesion Kinase and Inhibits Leptin-Induced Migration of MDA-MB-231 Breast Cancer Cells

cAMP Elevation Down-Regulates β3 Integrin and Focal Adhesion Kinase and Inhibits Leptin-Induced Migration of MDA-MB-231 Breast Cancer Cells

Breast cancer is one of the most common malignancies and a major cause of cancer death among women worldwide. The high mortality rate associated with breast cancer is mainly due to a propensity of the tumor to metastasize, even if small or undetectable. Given the relevant role of leptin in breast ca...

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Bibliographic Details
Main Authors: Spina, Annamaria, Di Maiolo, Francesca, Esposito, Antonietta, Sapio, Luigi, Chiosi, Emilio, Sorvillo, Luca, Naviglio, Silvio
Format: Online
Language:English
Published: Mary Ann Liebert, Inc. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559230/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559230/

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