Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity

► Efficient expression of FMDV empty capsids in insect cells after moderation of 3C protease action. ► Expression cassette productive in multiple insect cell lines. ► Empty capsids visualised by transmission electron microscopy. ► Empty capsids react with wide range of positive sera as well as authe...

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Bibliographic Details
Main Authors: Porta, Claudine, Xu, Xiaodong, Loureiro, Silvia, Paramasivam, Saravanan, Ren, Junyuan, Al-Khalil, Tara, Burman, Alison, Jackson, Terry, Belsham, Graham J., Curry, Stephen, Lomonossoff, George P., Parida, Satya, Paton, David, Li, Yanmin, Wilsden, Ginette, Ferris, Nigel, Owens, Ray, Kotecha, Abhay, Fry, Elizabeth, Stuart, David I., Charleston, Bryan, Jones, Ian M.
Format: Online
Language:English
Published: Elsevier/North-Holland Biomedical Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558679/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558679/

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