IL-18 Induces Airway Hyperresponsiveness and Pulmonary Inflammation via CD4+ T Cell and IL-13

IL-18 plays a key role in the pathogenesis of pulmonary inflammatory diseases including pulmonary infection, pulmonary fibrosis, lung injury and chronic obstructive pulmonary disease (COPD). However, it is unknown whether IL-18 plays any role in the pathogenesis of asthma. We hypothesized that overe...

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Bibliographic Details
Main Authors: Sawada, Masanori, Kawayama, Tomotaka, Imaoka, Haruki, Sakazaki, Yuki, Oda, Hanako, Takenaka, Shin-ichi, Kaku, Yoichiro, Azuma, Koichi, Tajiri, Morihiro, Edakuni, Nobutaka, Okamoto, Masaki, Kato, Seiya, Hoshino, Tomoaki
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558507/