Peripheral Nerve Injury Is Associated with Chronic, Reversible Changes in Global DNA Methylation in the Mouse Prefrontal Cortex

Changes in brain structure and cortical function are associated with many chronic pain conditions including low back pain and fibromyalgia. The magnitude of these changes correlates with the duration and/or the intensity of chronic pain. Most studies report changes in common areas involved in pain m...

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Bibliographic Details
Main Authors: Tajerian, Maral, Alvarado, Sebastian, Millecamps, Magali, Vachon, Pascal, Crosby, Cecilia, Bushnell, M. Catherine, Szyf, Moshe, Stone, Laura S.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557255/