Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans

Aging is associated chronic inflammation and autoimmunity, and increased levels of leptin. Increased levels of leptin are associated with inflammation and autoimmunity. We have recently reported that leptin activates B cells to induce secretion of proinflammatory and anti-inflammatory cytokines. Rol...

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Bibliographic Details
Main Authors: Gupta, Sudhir, Agrawal, Sudhanshu, Gollapudi, Sastry
Format: Online
Language:English
Published: BioMed Central 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557206/