FAS-Dependent Cell Death in α-Synuclein Transgenic Oligodendrocyte Models of Multiple System Atrophy

Multiple system atrophy is a parkinsonian neurodegenerative disorder. It is cytopathologically characterized by accumulation of the protein p25α in cell bodies of oligodendrocytes followed by accumulation of aggregated α-synuclein in so-called glial cytoplasmic inclusions. p25α is a stimulator of α-...

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Bibliographic Details
Main Authors: Kragh, Christine L., Fillon, Gwenaëlle, Gysbers, Amanda, Hansen, Hanne D., Neumann, Manuela, Richter-Landsberg, Christiane, Haass, Christian, Zalc, Bernard, Lubetzki, Catherine, Gai, Wei-Ping, Halliday, Glenda M., Kahle, Philipp J., Jensen, Poul H.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555893/