SB225002 Promotes Mitotic Catastrophe in Chemo-Sensitive and -Resistant Ovarian Cancer Cells Independent of p53 Status In Vitro

SB225002 Promotes Mitotic Catastrophe in Chemo-Sensitive and -Resistant Ovarian Cancer Cells Independent of p53 Status In Vitro

Recent evidence indicates that CXCR2 signaling is crucial for cancer progression, and its antagonist SB225002 induces apoptosis in Wilms’ tumor cells. Here, we investigated the effect of SB225002 on cell cycle progression and apoptosis induction in vitro, using CDDP-sensitive and -resistant OVCA cel...

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Bibliographic Details
Main Authors: Du, Meirong, Qiu, Qing, Gruslin, Andree, Gordon, John, He, Miao, Chan, Chi Chung, Li, Dajin, Tsang, Benjamin K.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554720/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554720/

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