Genetic and Functional Modularity of Hox Activities in the Specification of Limb-Innervating Motor Neurons

A critical step in the assembly of the neural circuits that control tetrapod locomotion is the specification of the lateral motor column (LMC), a diverse motor neuron population targeting limb musculature. Hox6 paralog group genes have been implicated as key determinants of LMC fate at forelimb leve...

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Bibliographic Details
Main Authors: Lacombe, Julie, Hanley, Olivia, Jung, Heekyung, Philippidou, Polyxeni, Surmeli, Gulsen, Grinstein, Jonathan, Dasen, Jeremy S.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554521/