Down-Regulation of CTLA-4 by HIV-1 Nef Protein

Down-Regulation of CTLA-4 by HIV-1 Nef Protein

HIV-1 Nef protein down-regulates several cell surface receptors through its interference with the cell sorting and trafficking machinery. Here we demonstrate for the first time the ability of Nef to down-regulate cell surface expression of the negative immune modulator CTLA-4. Down-regulation of CTL...

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Bibliographic Details
Main Authors: El-Far, Mohamed, Isabelle, Catherine, Chomont, Nicolas, Bourbonnière, Martin, Fonseca, Simone, Ancuta, Petronela, Peretz, Yoav, Chouikh, Younes, Halwani, Rabih, Schwartz, Olivier, Madrenas, Joaquín, Freeman, Gordon J., Routy, Jean-Pierre, Haddad, Elias K., Sékaly, Rafick-Pierre
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553160/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3553160/

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