A structural basis for streptomycin-induced misreading of the genetic code
During protein synthesis, the ribosome selects aminoacyl-tRNAs with anticodons matching the mRNA codon present in the A-site of the small ribosomal subunit. The aminoglycoside antibiotic streptomycin disrupts decoding by binding close to the site of codon recognition. Here we use X-ray crystallograp...
| Main Authors: | , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
2013
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552334/ |