STK295900, a Dual Inhibitor of Topoisomerase 1 and 2, Induces G2 Arrest in the Absence of DNA Damage

STK295900, a Dual Inhibitor of Topoisomerase 1 and 2, Induces G2 Arrest in the Absence of DNA Damage

STK295900, a small synthetic molecule belonging to a class of symmetric bibenzimidazoles, exhibits antiproliferative activity against various human cancer cell lines from different origins. Examining the effect of STK295900 in HeLa cells indicates that it induces G2 phase arrest without invoking DNA...

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Bibliographic Details
Main Authors: Kim, Sun-Ok, Sakchaisri, Krisada, N. R., Thimmegowda, Soung, Nak Kyun, Jang, Jae-Hyuk, Kim, Young Sang, Lee, Kyung Sang, Kwon, Yong Tae, Asami, Yukihiro, Ahn, Jong Seog, Erikson, Raymond Leo, Kim, Bo Yeon
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551932/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551932/

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