Potential use of Folate-appended Methyl-β-Cyclodextrin as an Anticancer Agent

To obtain a tumor cell-selectivity of methyl-β-cyclodextrin (M-β-CyD), we newly synthesized folate-appended M-β-CyD (FA-M-β-CyD), and evaluated the potential of FA-M-β-CyD as a novel anticancer agent in vitro and in vivo. Potent antitumor activity and cellular association of FA-M-β-CyD were higher t...

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Bibliographic Details
Main Authors: Onodera, Risako, Motoyama, Keiichi, Okamatsu, Ayaka, Higashi, Taishi, Arima, Hidetoshi
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551233/