Promoter Hypermethylation of ARID1A Gene Is Responsible for Its Low mRNA Expression in Many Invasive Breast Cancers

Promoter Hypermethylation of ARID1A Gene Is Responsible for Its Low mRNA Expression in Many Invasive Breast Cancers

ARID1A (AT-rich interactive domain 1A) has recently been identified as a tumor suppressor gene. Its mRNA expression is significantly low in many breast cancers; this is often associated with more aggressive phenotypes. However, the underlying molecular mechanism for its low expression has not been f...

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Bibliographic Details
Main Authors: Zhang, Xianyu, Sun, Qian, Shan, Ming, Niu, Ming, Liu, Tong, Xia, Bingshu, Liang, Xiaoshuan, Wei, Wei, Sun, Shanshan, Zhang, Youxue, Liu, Xiaolong Sean, Song, Qingbin, Yang, Yanmei, Ma, Yuyan, Liu, Yang, Yang, Long, Ren, Yanlv, Zhang, Guoqiang, Pang, Da
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549982/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549982/

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