The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain

The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain

The protease Sppl2a cleaves the N-terminal fragment of invariant chain (CD74) and is required for efficient B cell development and function.

Bibliographic Details
Main Authors: Beisner, Daniel R., Langerak, Petra, Parker, Albert E., Dahlberg, Carol, Otero, Francella J., Sutton, Sue E., Poirot, Laurent, Barnes, Whitney, Young, Michael A., Niessen, Sherry, Wiltshire, Tim, Bodendorf, Ursula, Martoglio, Bruno, Cravatt, Benjamin, Cooke, Michael P.
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549714/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549714/

Similar Items