Scribble is required for normal epithelial cell–cell contacts and lumen morphogenesis in the mammalian lung

During lung development, proper epithelial cell arrangements are critical for the formation of an arborized network of tubes. Each tube requires a lumen, the diameter of which must be tightly regulated to enable optimal lung function. Lung branching and lumen morphogenesis require close epithelial c...

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Bibliographic Details
Main Authors: Yates, Laura L., Schnatwinkel, Carsten, Hazelwood, Lee, Chessum, Lauren, Paudyal, Anju, Hilton, Helen, Romero, M. Rosario, Wilde, Jonathan, Bogani, Debora, Sanderson, Jeremy, Formstone, Caroline, Murdoch, Jennifer N., Niswander, Lee A., Greenfield, Andy, Dean, Charlotte H.
Format: Online
Language:English
Published: Elsevier 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549499/