The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction
Cells continuously sense and respond to external mechanical forces through their cytoskeleton. Here we show that only a small subset of actin fibers, those forming the perinuclear actin cap that wraps around the nucleus, form in response to low physiological mechanical stresses in adherent fibroblas...
Main Authors: | , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548190/ |