Up-regulation and Pre-activation of TRAF3 and TRAF5 in Inflammatory Bowel Disease

Objective: TRAF3 and TRAF5 share a common ancestral gene, and interact as essential components of signaling pathways in immunity. TRAF3 and TRAF5 are overexpressed in the colon of rat/mouse models with colitis. However, the expressions of TRAF3 and TRAF5 in patients with inflammatory bowel disease h...

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Bibliographic Details
Main Authors: Shen, Jun, Qiao, Yu-qi, Ran, Zhi-hua, Wang, Tian-rong
Format: Online
Language:English
Published: Ivyspring International Publisher 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547213/